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KMID : 0359920090280060658
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Korean Journal of Nephrology
2009 Volume.28 No. 6 p.658 ~ p.662
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A Case of Chronic Renal Failure in a Polydipsic Schizophrenic Patient caused by Chronic Anticholinergic Therapy
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Chon Il-Young
Oh Dong-Joon
Choi Seung-Jin
Kim Ji-Young
Ahn Ke-Ryun
Lee Won-Jun
Lee Ji-Yeon
Baek Hae-Ri
Lee Eun-Ji
Han Sang-Won
Lee Chan-Bok
Park Sang-Eun
Im Byoung-Kook
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Abstract
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Anticholinergic drugs block muscarinic receptors at the detrusor muscle of the bladder. It can cause urinary retention by contracting the bladder neck. Cases of hydronephrosis, bladder dilatation as a result of polydipsia while taking anticholinergic drugs have been reported, but very few cases of chronic renal failure can be found. We report a case of a polydipsic schizophrenic patient who, after taking anticholinergic drugs as antipsychotic drugs to treat his schizophrenia for a long time, presented with chronic renal failure due to functional obstructive uropathy in the absence of demonstrable anatomic causes of obstruction.
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KEYWORD
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Anticholinergics, Chronic renal failure, Urinary retention
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